Injectable Peptide Hormones Bodybuilding PEG-MGF PEGylated Mechano
Molecular Formula : C121H200N42O39
Molecular Weight : 2867.2
CAS No. : N/A
PEG-MGF, or PEGylated Mechano Growth Factor is a new and innovative
form of MGF that outperforms natural MGF many times over. MGF is a
splice variant of the IGF gene which increases stem cell count in
the muscle and allows for muscle fibers to fuse and mature. This is
a process required for growth of adult muscle. Natural MGF is made
locally and does not travel into the bloodstream. Synthetic MGF is
water based and when administered intramuscularly, travels into the
bloodstream. MGF is only stable in the blood stream for only a few
PEGylation is the act of attaching a Polyethylene glycol (PEG)
structure to another larger molecule (in this case, MGF). The PEG
acts as a protective coating and the theory here is that this will
allow the MGF to be carried through the blood stream without being
MGF exhibits local effects in skeletal muscle and without cannot
travel through the body without modification. The problem with
synthetic MGF is that it is introduced intramuscularly and is water
based so it goes into the blood stream. When used this way, MGF
only remains stable in the blood stream for a few minutes.
Biologically produced MGF is made locally and does not enter the
bloodstream. It is also short acting so stability is not an issue.
By PEGylating the MGF it is almost as efficient as local produced
MGF when used intramuscularly. This is accomplished by surrounding
part of the peptide with a structure of polyethylene glycol, which
can be attached to a protein molecule. The polyethylene glycol
groups protect the peptide but don’t surround it completely. The
active sites of the peptide are still free to do their biological
function. In this case the shell is a negative charged shield
against positively charged compounds that would affect the protein.
Neurological research has shown that utilizing PEGylated MGF
resulted in a longer more stable acting version of the MGF peptide
Why Mechano Growth Factor? Resistance training or more
specifically, a training that causes our muscles to work beyond
their usual power leads to that familiar ‘burning’ sensation we all
have had a chance to experience during an exercise. What happens to
our muscles at that point is the following: Every muscle is a
cluster of muscle fibers (muscle cells), which at the point of
extreme efforts tend to tear. The tearing of the muscle fibers is
what causes the burning sensation. The torn parts form certain
‘cavities’ in the muscle tissue and those cavities represent a
chance for a muscle to grow. After those ‘cavities’ are filled up
with the muscle ‘matter’, we are left with a muscle of an increased
mass. Why ‘Mechano’? Because tearing of the muscle fibers is an
actual mechanical damage, and the only way to achieve that kind of
damage is through mechanical stimulation of the muscle tissue. Why
‘Growth Factor’? Because Mechano Growth Factor is responsible for
accelerated muscle build-up processes. Besides accelerating muscle
build-up processes Mechano Growth Factor also helps create new
muscle cells. That’s a simplified way of looking at the whole
We will explain a few more details behind the workings of the
Mechano Growth Factor and PEG-MGF shortly.
Mechano Growth Factor is a peptide hormone, a natural physiological
byproduct created in a human body as a result of an exercise.
Mechano Growth Factor (MGF) and IGF-1 (Insulin-like Growth Factor)
are isoforms. Isoform is a protein with a slightly different form
but usually a similar function as its ‘fellow’ isoform protein.
Both, MGF (which is a liver derived hormone) and IGF-1 (which is
produced in the muscles) have anabolic effects, but the anabolic
powers of the MGF are greater than those of IGF-1. Anabolic quality
of a substance is such that increases the levels of synthesis,
either at a molecular or a cellular level, meaning the Mechano
Growth Factor has a greater sensitivity to damages caused to
muscles by exercise and induces the synthesis of a greater amount
of proteins in skeletal muscles.
Another favorable effect of the Mechano Growth Factor is its
ability to activate the satellite cells of muscles (myosatellite
cells). Myosatellite cells behave as stem cells. Once they are
activated they fuse, form myoblastst, proceed to differentiate and
form entirely new muscle cells. Again, the result is muscle growth.
But what about PEG-MGF? Why do we at BeFit4Free produce the
PEGylated version of the Mechano Growth Factor if the MGF on its
own has so much potential anyway?
PEGylated protein (PEG-MGF) is the one that has Polyethylene Glycol
added to it. The role of the Polyethylene Glycol molecule is to
preserve the integrity of the Mechano Growth Factor. Unlike the
naturally produced Mechano Growth Factor, the injected MGF needs to
enter the circulatory system. That is where the problem for the MGF
arises. MGF is not stable in such environment and in order to be
able to reach its final destination and fulfill its role it needs
to be PEGylated (and turned into PEG-MGF). Polyethylene Glycol
serves as a kind of a shell protecting the MGF from reacting to its
surroundings before it reaches its final destination. It makes the
PEG-MGF much more stable and long-lasting than Machano Growth
Factor could be on its own.
PEG MGF Dosage:
Typical dosage of PEG-MGF is between 200mcg. – 400mcg. per week but
many bodybuilders have said to “research” this peptide at dosages
exceeding 1,500 mcg weekly with no adverse effects.
Because PEG MGF can cause site specific muscle growth, it is
recommended to inject PEG MGF bi-laterally to ensure symmetrical
gains. The most effective test results were experienced in users
injecting the PEG MGF post exercise.
Delivery and shipping:
1. We will ship the goods within 1-2 days after payment.
2. We will ship the goods by UPS,EMS,DHL, TNT or FEDEX . We will
choose the best courier depend on Different countries, and find the
safe way to deliver the goods for you.
3. Like Russia, Australia, Canada, customs is very strict, but we
can ensure 100% delivery.
4. As usual you can get the goods with in 4-7days. If the goods
were lost or not received for other reasons, we'll resend.
We have many regular customers worldwide, and hope to establish
long-term cooperation with you, For further informations please
feel free to contact us, we’ll do our best to fulfill your request.