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China High Quality API Repaglinide (CAS: 135062-02-1)

Categories Bulk Drug
Model Number: Pharmaceutical Raw Materials
Certification: SGS
Place of Origin: Hubei, China
MOQ: 100g
Payment Terms: L/C, T/T
Packaging Details: Aluminum Foil Bags or Fiber Drum.
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    China High Quality API Repaglinide (CAS: 135062-02-1)

    China High Quality API Repaglinide
    (CAS: 135062-02-1)

    Quick Details:
    Name Repaglinide
    Synonyms (S)-(+)-2-Ethoxy-4-[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]aminocarbonylmethyl]benzoic acid; Novonorm; Prandin
    MF C27H36N2O4
    MW 452.59
    CAS 135062-02-1
    Quality Standard EP/USP
    Delivery Date 7-12 days
    Application Pharmaceutical raw materials

    Product Description:
    Repaglinide lowers blood glucose by stimulating the release of insulin from the pancreas. It achieves this by closing ATP-dependent potassium channels in the membrane of the beta cells. This depolarizes the beta cells, opening the cells' calcium channels, and the resulting calcium influx induces insulin secretion.
    Other name: 4-Ethoxycarbonyl-3-ethoxy phenyl acetic acid; (S)-(+)-2-Ethoxy-4-[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]aminocarbonylmethyl]benzoic acid; 2-ethoxy-4-[2-({3-methyl-1-[2-(piperidin-1-yl)phenyl]butyl}amino)-2-oxoethyl]benzoic acid; 2-ethoxy-4-[2-({(1S)-3-methyl-1-[2-(piperidin-1-yl)phenyl]butyl}amino)-2-oxoethyl]benzoic acid

    CAS NO.: 135062-02-1

    MF: C27H36N2O4

    MW: 452.5857

    InChI: 1/C27H36N2O4/c1-4-33-25-17-20(12-13-22(25)27(31)32)18-26(30)28-23(16-19(2)3)21-10-6-7-11-24(21)29-14-8-5-9-15-29/h6-7,10-13,17,19,23H,4-5,8-9,14-16,18H2,1-3H3,(H,28,30)(H,31,32)/t23-/m0/s1

    Melting point: 129-130°C

    Boiling point: 672.9°C at 760 mmHg

    Flash point: 360.8°C

    Density: 1.137g/cm3

    Standard: USP/BP/CP/EP

    Odor: odorless





    Off white crystalline powder
    Off white crystalline powder


    Infared Absorption


    The retention time of the major peak

    in the chromatogram of the

    Assay prepration corresponds to that in

    the chromatogram of the standard preparation,

    as obtained in the assay


    Specific rotation

    Between -28.6°and -35.0°, measured at 20°



    not more than 0.5%


    residue on ignition

    not more than 0.2%


    Heavy metals

    not more than 0.001%


    related compounds
    by HPLC

    Fructose not more than 0.3% Compound

    A not more than 0.3% Other individual impurity not more than 0.1%

    Total impurities not more than 0.5%

    Fructose: 0.03% Compound A: 0.04%

    Total impurities: 0.07%

    Particle size

    90% less than 350 microns


    Residual Solvent

    Methylene Chloride not more than 250μg/g

    not detected

    Acetone not mor than 2500μg/g

    Isopropanol not more than 5000μg/g

    Ethanenitrile not more than 400μg/g

    n-hexane not more than 290μg/g

    Ethyl Acetate not more than 2500μg/g

    Pyridine not more than 100μg/g


    Topiramate contains not less than 98.0% and

    not more than the equivalent of 102.0% of C12H21NO8S, calculated with reference to the Anhydrous Basis



    The material complies with respect to USP32

    Wuhan Newbio Pharm-tech Co., Ltd.
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    #1 We are manufacturer with own factory and we sale this product at a best quality and low price.
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